Peptide Reconstitution Calculator
Draw this amount:10units
Concentration2.5 mg/mL
Volume to inject0.10 mL
Doses per vial20
How to Use This Peptide Calculator
1
Enter Peptide Amount
Input the total milligrams (mg) in your peptide vial. Common sizes: 2mg, 5mg, 10mg.
2
Add Water Volume
Enter how much bacteriostatic water (BAC water) you'll add. More water = easier to measure small doses.
3
Set Your Dose
Enter your desired dose in micrograms (mcg). The calculator shows exact syringe units to draw.
How Cagrilintide Is Dosed
Cagrilintide is a long-acting amylin analog developed as a once-weekly subcutaneous injection, and it is the amylin partner of semaglutide in the investigational combination known as CagriSema.
Its long duration comes from a measured terminal half-life of roughly 7 to 8 days (about 159 to 195 hours across the 0.16 to 4.5 mg dose range) reported in Novo Nordisk phase 1b pharmacokinetic work (Enebo et al., Lancet 2021, PMID 33894838). That half-life is what supports once-weekly dosing.
Because cagrilintide is measured in milligrams and titrated slowly, most people reconstitute a 5 mg or 10 mg vial and draw a fraction of it each week. The calculator above converts any mg dose into the exact units on a U-100 insulin syringe.
Cagrilintide is a research compound. The doses shown are drawn from published trials or community protocols and are not clinically validated for self-administration. This tool is educational only and is not medical advice or a dosing recommendation.
Cagrilintide Dosing Reference
| Peptide | Common Vial | Cited Dose | BAC Water | Units to Draw |
|---|---|---|---|---|
| Cagrilintide | 10mg | 2.4mg | 2mL | 48 units |
| Cagrilintide | 5mg | 0.3mg | 2mL | 12 units |
| Semaglutide | 5mg | 250mcg | 2mL | 10 units |
Cited from phase 1b trial doses (0.16 to 4.5 mg weekly). Not a recommendation. Verify with your own protocol.
The Math Behind Peptide Reconstitution
Concentration formula:
Concentration (mg/mL) = Peptide (mg) ÷ Water (mL)Units to draw:
Units = [Dose (mcg) ÷ 1000] ÷ Concentration × 100Example: BPC-157 250mcg dose
- 5mg vial + 2mL BAC water = 2.5 mg/mL
- 250mcg = 0.25mg
- 0.25mg ÷ 2.5 mg/mL = 0.10mL
- 0.10mL × 100 = 10 units on insulin syringe
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Discover Peptide LabUnderstanding Insulin Syringe Units
10 units = 0.10 mL
Quick Reference
- 100 units = 1 mL (full syringe)
- 50 units = 0.5 mL (half syringe)
- 10 units = 0.1 mL (1/10th syringe)
- 1 unit = 0.01 mL
Standard insulin syringes are U-100, meaning 100 units per mL. This calculator uses this standard.
Frequently Asked Questions
What is the half-life of cagrilintide?
Published phase 1b pharmacokinetic data report a terminal half-life of roughly 7 to 8 days (about 159 to 195 hours), which is why cagrilintide is dosed once weekly (Enebo et al., Lancet 2021, PMID 33894838).
What doses of cagrilintide have been studied?
Phase 1b work studied weekly subcutaneous doses from 0.16 mg up to 4.5 mg. In the CagriSema combination, 2.4 mg weekly is the commonly referenced dose. These are trial doses, not a recommendation.
Why is cagrilintide dosed weekly instead of daily?
Its long half-life of about a week means one injection maintains exposure across seven days, so weekly dosing is enough. This is the same rationale as other long-acting weekly peptides.
Is cagrilintide the same as semaglutide?
No. Semaglutide is a GLP-1 receptor agonist and cagrilintide is an amylin analog. They act on different pathways and are studied together as the combination CagriSema, but they are separate molecules.
What is bacteriostatic water (BAC water)?
Bacteriostatic water is sterile water containing 0.9% benzyl alcohol as a preservative. It prevents bacterial growth, allowing multi-use of reconstituted peptides for 4-6 weeks when refrigerated.
How much water should I add to my vial?
Common choices are 1mL, 2mL, or 3mL. More water makes small doses easier to measure accurately but means larger injection volumes. 2mL is a good balance for most peptides.
What does "units" mean on an insulin syringe?
Insulin syringes use "units" as measurements. Standard U-100 syringes have 100 units per 1mL, so 10 units = 0.10mL and 50 units = 0.50mL.
How long do reconstituted peptides last?
With bacteriostatic water, most peptides remain stable for 4-6 weeks when refrigerated at 2-8 degrees Celsius. With sterile water (no preservative), use within 24-48 hours.
Is this calculator free to use?
Yes, completely free with no signup required. For injection tracking, body maps and protocol management, see our full Peptide Lab app.